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FOX SEGMENT — before Deadpool & Wolverine and Avengers: Doomsday
1994X-Men 2MOVIE
1999
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2013The WolverineMOVIE

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Good to know

When does X-Men: The Last Stand take place in the MCU?

Although released in the 2000s and normally set around the same time, the X-Men universe's timeline is a glorious mess full of inconsistencies, and the movie works more logically in 1999, 5 years after the previous movie

How is X-Men: The Last Stand connected to the MCU?

The movie takes place in a parallel universe, and some of its characters will appear in Deadpool & Wolverine as well as Avengers: Doomsday

Why watch X-Men: The Last Stand at this point in the timeline?

Because watching these movies at their actual in-universe point would make no sense, and I think the events of Loki matter — as does having everything fresh in your head before Deadpool & Wolverine and Avengers: Doomsday

What about the post-credits scene(s)?

The post-credits scene is very important but hard to understand since they give zero details, so SPOILER warning: Charles Xavier had a brain-dead twin brother, and upon dying he transferred his mind into his brother's body

Where does X-Men: The Last Stand fit in Marvel?